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北京地下直径线大直径盾构隧道技术研究

索晓明,张继清,杨毅秋

《中国工程科学》 2010年 第12卷 第12期   页码 11-17

摘要:

以北京地下直径线双线大直径(Ø11.6 m)盾构隧道的设计技术研究为背景,重点介绍了该盾构隧道的盾构选型、盾构管片结构计算、管片结构设计、管片防水设计等技术,并对该盾构隧道施工的设计要求做了简单叙述,对今后类似工程具有一定参考价值。

关键词: 铁路隧道     大直径盾构     管片设计    

Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder cancer cell in vitro

FAN Xiaodong, HAN Ruifa

《医学前沿(英文)》 2007年 第1卷 第4期   页码 377-380 doi: 10.1007/s11684-007-0073-8

摘要: Presently, one of the most potent immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladder cancer. Despite its successful use, nonresponders and certain side effects remain a major obstacle. Therefore, current studies aim at developing recombinant BCG (rBCG) strains secreting Th1-like cytokines to improve the effectiveness of the therapy. In this study, a new type of rBCG strain constructed by Tianjin institute of Urology was tested for its immunostimulatory capacity . Peripheral blood monocytes (PBMC) were stimulated by recombinant BCG and transformed into bacilli Calmette–Guerin activated killer (BAK) cells, and the effect of anticancer BAK cells was studied. Recombinant IFN--2b-BCG, wild-type BCG (wBCG), wild-type BCG and IFN--2b were coincubated with PBMCs respectively , and the proliferation of PBMC was detected with MTT in different time. BAK cells have the ability to kill bladder tumor cells, and the antitumor activity of effecter cells was determined by LDH release assay. The result of MTT showed that the proliferation of PBMC in the recombinant BCG group was more powerful than in the other two groups (<0.05). The result of LDH release assay showed that the antitumor activity of BAK cells stimulated by Recombinant BCG was the highest in all groups. We conclude that the recombinant BCG can activate more PBMCs to anti-bladder cancer than wild-type BCG does.

关键词: Urology     powerful     2b-BCG     Tianjin institute     wild-type    

The Effect of TRIZ on Research Institute Innovation

He Liu,Qing-hai Yang,Xu Jin

《工程管理前沿(英文)》 2014年 第1卷 第4期   页码 385-389 doi: 10.15302/J-FEM-2014059

摘要: With a background in improving independent innovation capabilities and building a world-class petroleum research institute, scientific innovation is the essence and basis of an innovative framework for a research institute, as well as the inexhaustible driving force for sustainable development. By introducing the theory of inventive problem solving (TRIZ) and combining it with CAI (computer aided innovation) technology, the Research Institute of Petroleum Exploration and Development established an adaptive innovative system by making experiments and fanning out from a point to an area gradually. This article takes the example of the innovative practices of the Department of Petroleum Equipment in Research Institute of Petroleum Exploration and Development, and introduces a building method for the innovative system based on technical innovation, enterprise culture, organizational structure, scheme, and people. It also summarizes the experiences and effects of improving innovative system upon scientific practice which can provide important guidance and reference significance for accelerating independent innovative capability.

关键词: innovative capability     TRIZ theory     petroleum equipment     research institute     innovative system    

Energy consumption of 270 schools in Tianjin, China

Jincheng XING,Junjie CHEN,Jihong LING

《能源前沿(英文)》 2015年 第9卷 第2期   页码 217-230 doi: 10.1007/s11708-015-0352-z

摘要: With the rapid development of education cause, the increasing energy consumption of school buildings is gradually causing widespread concern in recent years in China. This paper presented an analysis of energy consumption of 270 schools located in the city of Tianjin, China. The analysis focused specifically on calculating the space heating energy consumption indexes and non-heating energy consumption indexes of different types of schools, aiming at providing reliable and precise data for the government to elaborate policies and measures. The space heating energy consumption of schools adopting district heating and gas boiler were 92.04 kWh/(m ·a) and 64.25 kWh/(m ·a), respectively. Comparing to the schools without a canteen, the non-heating energy consumption index of schools with a canteen can increase by 8%–37%. Furthermore, clustering of different energy sources, the total primary energy consumption indexes were also presented. Space heating energy consumption accounted for approximately 64%–79% of the total primary energy consumption. When using time-sharing control and self-contained gas boiler instead of district heating, an amount of almost 27.8 kWh/(m ·a) and 77.5 kWh/(m ·a) can be saved respectively. Through extensive statistical analysis of the data collected, this paper demonstrated that gross floor area, heating energy source and canteen had a close relationship with the total primary energy consumption regarding complete schools. Eventually, a linear regression equation was established to make a simple prediction about the total energy consumption of existing complete schools and to estimate the energy consumption of complete schools to be built.

关键词: schools     energy consumption index     primary energy     energy saving     regression analysis    

京津城际铁路科技创新

何华武

《中国工程科学》 2009年 第11卷 第1期   页码 4-16

摘要:

高速铁路是复杂的巨系统。京津城际铁路是我国首条工程实践、运营实践的高速铁路,在攻克系统设计与系统集成、轨道高平顺与高稳定、高速列车安全与舒适、运行(营)控制可靠与高效四大方面科技难题和关键技术取得了重大创新成果;历时3年建造,开通运营验证,整体达到世界领先水平;该成果对推进我国铁路网又好又快地建设具有指导性、示范性的重大作用。

关键词: 高速铁路     京津城际     创新成果     示范引领    

Seismic vulnerability assessment of water supply network in Tianjin, China

Yanxi CHEN,Zhiguang NIU,Jiaqi BAI,Yufei WANG

《环境科学与工程前沿(英文)》 2014年 第8卷 第5期   页码 767-775 doi: 10.1007/s11783-014-0632-6

摘要: The water supply network (WSN) system is a critical element of civil infrastructure systems. Its complexity of operation and high number of components mean that all parts of the system cannot be simply assessed. Earthquakes are the most serious natural hazard to a WSN, and seismic risk assessment is essential to identify its vulnerability to different stages of damage and ensure the system safety. In this paper, using a WSN located in the airport area of Tianjin in northern China as a case study, a quantitative vulnerability assessment method was used to assess the damage that the water supply pipelines would suffer in an earthquake, and the finite element software ABAQUS and fuzzy mathematic theory were adopted to construct the assessment method. ABAQUS was applied to simulate the seismic damage to pipe segments and components of the WSN. Membership functions based on fuzzy theory were established to calculate the membership of the components in the system. However, to consider the vulnerability of the whole system, fuzzy cluster analysis was used to distinguish the importance of pipe segments and components. Finally, the vulnerability was quantified by these functions. The proposed methodology aims to assess the performance of WSNs based on pipe vulnerabilities that are simulated and calculated by the model and the mathematical method based on data of damage. In this study, a whole seismic vulnerability assessment method for a WSN was built, and these analyses are expected to provide necessary information for a mitigation plan in an earthquake disaster.

关键词: water supply network     seismic vulnerability assessment     finite element     fuzzy mathematics    

A glance of excellence in chemical science and engineering at Tianjin University: A special issue dedicated

《化学科学与工程前沿(英文)》 2015年 第9卷 第3期   页码 259-261 doi: 10.1007/s11705-015-1537-z

evaluation of government investment for air pollution control in city clusters: A case from the Beijing–Tianjin–Hebei

《工程管理前沿(英文)》   页码 612-624 doi: 10.1007/s42524-023-0269-x

摘要: Air pollution poses a significant threat to human health, particularly in urban areas with high levels of industrial activities. In China, the government plays a crucial role in managing air quality through the Air Pollution Prevention and Control Action Plan. The government provides direct financial support and guides the investment direction of social funds to improve air quality. While government investment has led to improvements in air quality across China, concerns remain regarding the efficiency of such large-scale investments. To address this concern, we conducted a study using a three-stage data envelopment analysis (DEA)-Malmquist model to assess the efficiency of government investment in improving air quality in China. Our analysis revealed regional disparities and annual dynamic changes. Specifically, we focused on the Beijing–Tianjin–Hebei areas as a case study, as the investment primarily targeted industrial activities in urban areas with the goal of improving living conditions for urban residents. The results demonstrate significant differences in investment efficiency between regions. Beijing exhibits relatively high investment efficiency, while cities in Hebei Province require improvement. We identified scale inefficiency, which refers to the ratio of air pollutant reduction to financial investment, as the main factor contributing to regional disparities. However, we found that increasing the total investment scale can help mitigate this effect. Furthermore, our study observed positive but fluctuating annual changes in investment efficiency within this city cluster from 2014 to 2018. Investment-combined technical efficiency, which represents the investment strategy, is the main obstacle to improving yearly investment efficiency. Therefore, in addition to promoting investment strategies at the individual city level, it is crucial to enhance coordination and cooperation among cities to improve the investment efficiency of the entire city cluster. Evaluating the efficiency of government investment and understanding its influencing factors can guide future investment measures and directions. This knowledge can also support policymaking for other projects involving substantial investments.

关键词: investment efficiency     government investment     air pollution control     three-stage DEA-Malmquist model    

奋进中的上海石油化工研究院

《中国工程科学》 2002年 第4卷 第6期   页码 92-93

科技创造卓越——飞速发展的长沙矿冶研究院

《中国工程科学》 2001年 第3卷 第8期   页码 93-94

京津城际铁路桥梁沉降观测与评估技术

丁愿文

《中国工程科学》 2009年 第11卷 第1期   页码 43-47

摘要:

以京津城际铁路工程为例,系统地介绍了无碴轨道客运专线(高速铁路)桥梁沉降观测的具体要求、方法,并提出了沉降评估的数学模型和判定条件。

关键词: 京津城际铁路     桥梁     沉降观测     评估    

向世界一流迈进的石油化工科学研究院

null

《中国工程科学》 2001年 第3卷 第3期   页码 92-93

广州有色金属研究院卅年科技创新谱新篇

《中国工程科学》 2002年 第4卷 第3期   页码 92-94

interval joint-probabilistic programming method for solid waste management: a case study for the city of Tianjin

Yi XU, Shunze WU, Hongkuan ZANG, Guiguang HOU

《环境科学与工程前沿(英文)》 2014年 第8卷 第2期   页码 239-255 doi: 10.1007/s11783-013-0536-x

摘要: Currently, environmental protection and resources conservation continue to be challenges faced by solid-waste managers in China. These challenges are being further compounded by rapid socioeconomic development and population growth associated with increased waste generation rates and decreased waste disposal capacities. In response to these challenges, an interval joint-probabilistic mixed-integer programming (IJMP) method is developed for supporting long-term planning of waste management activities in the city of Tianjin, which is one of the largest municipalities in the northern part of China. In the IJMP, joint probabilistic constraints are introduced into an interval-parameter mixed-integer programming framework, such that uncertainties presented in terms of interval values and random variables can be reflected. Moreover, a number of violation levels for the waste-management-capacity constraints are examined, which can facilitate in-depth analyses of tradeoffs among economic objective and system-failure risk. The results indicate that reasonable solutions have been generated. They are valuable for supporting the adjustment of the city’s existing waste-management practices and the long-term planning of the city’s waste-management facilities.

关键词: interval analysis     mixed integer     joint probabilistic constraint     planning     uncertainty     waste management    

中国石油化工股份有限公司抚顺石油化工研究院

《中国工程科学》 2001年 第3卷 第6期   页码 93-94

标题 作者 时间 类型 操作

北京地下直径线大直径盾构隧道技术研究

索晓明,张继清,杨毅秋

期刊论文

Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder cancer cell in vitro

FAN Xiaodong, HAN Ruifa

期刊论文

The Effect of TRIZ on Research Institute Innovation

He Liu,Qing-hai Yang,Xu Jin

期刊论文

Energy consumption of 270 schools in Tianjin, China

Jincheng XING,Junjie CHEN,Jihong LING

期刊论文

京津城际铁路科技创新

何华武

期刊论文

Seismic vulnerability assessment of water supply network in Tianjin, China

Yanxi CHEN,Zhiguang NIU,Jiaqi BAI,Yufei WANG

期刊论文

A glance of excellence in chemical science and engineering at Tianjin University: A special issue dedicated

期刊论文

evaluation of government investment for air pollution control in city clusters: A case from the Beijing–Tianjin–Hebei

期刊论文

奋进中的上海石油化工研究院

期刊论文

科技创造卓越——飞速发展的长沙矿冶研究院

期刊论文

京津城际铁路桥梁沉降观测与评估技术

丁愿文

期刊论文

向世界一流迈进的石油化工科学研究院

null

期刊论文

广州有色金属研究院卅年科技创新谱新篇

期刊论文

interval joint-probabilistic programming method for solid waste management: a case study for the city of Tianjin

Yi XU, Shunze WU, Hongkuan ZANG, Guiguang HOU

期刊论文

中国石油化工股份有限公司抚顺石油化工研究院

期刊论文